5-(2-Pyrrolidin-1-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine
5-(2-Pyrrolidin-1-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine
CAS: 14069-13-7
Molecular Formula: C8H14N4S
5-(2-Pyrrolidin-1-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine - Names and Identifiers
5-(2-Pyrrolidin-1-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine - Physico-chemical Properties
| Molecular Formula | C8H14N4S |
| Molar Mass | 198.29 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD07186497 |
5-(2-Pyrrolidin-1-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
5-(2-Pyrrolidin-1-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine - Introduction
5-(+)-[1,3,4]thiadiazol-2-ylamine is an organic compound with the formula C9H15N5S.
Nature:
-Appearance: Colorless to light yellow solid
-melting point: about 108-110 ℃
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide
Use:
- 5-()-[1,3,4]thiadiazol-2-ylamine can be used as an organic synthesis intermediate for the synthesis of other compounds.
-In the field of medicine, it may have anti-tumor, anti-inflammatory and antibacterial activities, so it can be used as a candidate substance for drug development.
Preparation Method:
At present, there are few detailed literature reports on the preparation method of 5-(1,3,4)-[1,3,4]thiadiazol-2-ylamine, but a possible synthetic route includes the following steps:
1. The reaction of 2-amino -1,3,4-thiadiazole with α-halogenated ketones under alkaline conditions produces the corresponding products.
2. Next, react with 2-bromoethylpyrrolidine through an amide coupling reaction to form 5-(¾)-[1,3,4]thiadiazol-2-ylamine.
Safety Information:
Due to the limited information on the specific safety of the 5-()-[1,3,4]thiadiazol-2-ylamine, strict compliance with relevant safety regulations for general chemical use is required. Wear appropriate personal protective equipment to avoid contact with skin and eyes. Regulations on laboratory safety and waste disposal must be observed during operation. For further use of this compound, it is recommended to refer to the relevant literature and consult a professional for more detailed safety information.
Nature:
-Appearance: Colorless to light yellow solid
-melting point: about 108-110 ℃
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide
Use:
- 5-()-[1,3,4]thiadiazol-2-ylamine can be used as an organic synthesis intermediate for the synthesis of other compounds.
-In the field of medicine, it may have anti-tumor, anti-inflammatory and antibacterial activities, so it can be used as a candidate substance for drug development.
Preparation Method:
At present, there are few detailed literature reports on the preparation method of 5-(1,3,4)-[1,3,4]thiadiazol-2-ylamine, but a possible synthetic route includes the following steps:
1. The reaction of 2-amino -1,3,4-thiadiazole with α-halogenated ketones under alkaline conditions produces the corresponding products.
2. Next, react with 2-bromoethylpyrrolidine through an amide coupling reaction to form 5-(¾)-[1,3,4]thiadiazol-2-ylamine.
Safety Information:
Due to the limited information on the specific safety of the 5-()-[1,3,4]thiadiazol-2-ylamine, strict compliance with relevant safety regulations for general chemical use is required. Wear appropriate personal protective equipment to avoid contact with skin and eyes. Regulations on laboratory safety and waste disposal must be observed during operation. For further use of this compound, it is recommended to refer to the relevant literature and consult a professional for more detailed safety information.
Last Update：2024-04-09 21:04:16
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5-(2-Pyrrolidin-1-yl-ethyl)-[1,3,4]thiadiazol-2-ylamine
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2,2'-(6,6'-Bibenzothiazole-2,2'-diyl)bis(1-amino-9,10-anthraquinone)
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Diethyl butylmalonate
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2-chloro-6-ethoxy-3-(1-(methylsulfonyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-5-yl)quinoline
DDE-D-LYS(ALLOC)-OH
3-[1,2,4]Triazolo[3,4-b][1,3,4]thiadiazol-6-yl-phenylamine